Question: What Are The Main Parts Of The Juxtaglomerular Apparatus?

What are the three components of the Juxtaglomerular apparatus?

The three cellular components of the apparatus are the macula densa, extraglomerular mesangial cells, and juxtaglomerular cells (also known as granular cells)[WP]..

What is the function of the Juxtaglomerular apparatus quizlet?

Macula Densa & Juxtaglomerular cells. What is the main function of the Juxtaglomerular apparatus? To secrete Erythropoitein and Renin.

Which is the most direct function of the Juxtaglomerular apparatus?

The structure of the juxtaglomerular apparatus is a formed by the distal convoluted tubule and the afferent glomerular arteriole and it helps in the regulation of blood pressure and glomerular filtration rate (volume of blood filtered by the kidney’s into the Bowman’s capsule per unit of time).

What three driving forces determine glomerular filtration rate?

glomerular filtration rate (GFR) – The total amount of plasma filtrate formed by all the nephrons of the kidneys per minute; it is determined physiologically by three factors: (1) the total surface area available for filtration, (2) the permeability of the filtration membrane, and (3) the net filtration pressure; …

What hormone is secreted by the juxtaglomerular apparatus?

ReninRenin is produced by juxtaglomerular cells. These cells are similar to epithelium and are located in the tunica media of the afferent arterioles as they enter the glomeruli. The juxtaglomerular cells secrete renin in response to: Stimulation of the beta-1 adrenergic receptor.

Which structure is most important for urine concentration?

Which structure is most important for urine concentration? Capsular hydrostatic pressure is the chief force pushing water and solutes out of the blood and across the filtration membrane.

What should not be found in filtrate?

Blood proteins and blood cells are too large to pass through the filtration membrane and should not be found in filtrate. Tubular reabsorption begins in the glomerulus.

What is the Juxtaglomerular apparatus?

The juxtaglomerular apparatus is the location of renin-secreting cells and the macula densa and lies at the junction between the loop of Henle and the distal nephron at which the tubule comes in close proximity to the afferent arteriole.16.

What activates Juxtaglomerular cells?

Juxtaglomerular Cells Although they are activated by prostaglandins released from the macula densa cells, they can also release renin independently of the macula densa. Baroreceptors found in the arterioles trigger renin secretion if there is a fall in blood pressure in the arterioles.

What enzyme is released by the Juxtaglomerular complex to regulate GFR?

ReninRenin is an enzyme that is produced by the granular cells of the afferent arteriole at the juxtaglomerular apparatus.

What are the 2 types of nephrons?

Key PointsKidneys contain two types of nephrons, each located in different parts of the renal cortex: cortical nephrons and juxtamedullary nephrons.A nephron comprises a renal corpuscle, a renal tubule, and the associated capillary network.More items…•

Why is Vasa recta absent in cortical nephron?

The proximity between the Henle’s loop and vasa recta, as well as the counter current in them help in maintaining an increasing osmolarity towards the inner medullary interstitium. This gradient is mainly caused by NaCl and urea. … This mechanism helps to maintain a concentration gradient in the medullary interstitium.

What is the function of the Juxtaglomerular cells?

The afferent arteriole in this region contains specialised secretory cells (smooth muscle cells) called juxtaglomerular cells, that secrete renin. These cells do two things: They monitor blood pressure, by measuring how much the arteriole wall is stretched.

What stimulates the release of renin from the juxtaglomerular apparatus?

Juxtaglomerular (JG) cells associated with the afferent arteriole entering the renal glomerulus are the primary site of renin storage and release. A reduction in afferent arteriole pressure causes the release of renin from the JG cells, whereas increased pressure inhibits renin release.

What are the parts of the Juxtaglomerular apparatus?

The juxtaglomerular apparatus consists of the juxtaglomerular cells of the afferent glomerular arteriole, the efferent glomerular arteriole, the extraglomerular mesangial cells, and that small portion of the distal tubule known as the macula densa that is located beside the renal glomerulus.

What is the Juxtamedullary nephron?

In other words, a juxtamedullary nephron is a nephron whose renal corpuscle is near the medulla, and whose proximal convoluted tubule and its associated loop of Henle occur deeper in the medulla than the other type of nephron, the cortical nephron.

What activates JGA release renin?

The juxtaglomerular cells are also stimulated to release renin by signaling from the macula densa. The macula densa senses changes in sodium delivery to the distal tubule, and responds to a drop in tubular sodium load by stimulating renin release in the juxtaglomerular cells.

What stimulates macula densa cells?

The cells of the macula densa are sensitive to the concentration of sodium chloride in the distal convoluted tubule. … As such, an increase in sodium chloride concentration would result in vasoconstriction of afferent arterioles, and reduced paracrine stimulation of juxtaglomerular cells.

What is the renal corpuscle made of?

The nephron is composed of renal corpuscle and renal tubule and is the functional unit of the kidney. The renal corpuscle consists of Bowman’s capsule and glomerular capillaries, responsible for plasma filtration (image A) & (image B). Network of capillaries that invaginate into Bowman’s capsule.

Is nephron a cell?

are nephrons cells or tissues? … The nephron is the functional unit of the kidney that is made up of cells. So, it is tissue. Comment on Abid Ali’s post “The nephron is the functional unit of the kidney t…”

What stimulates JG cells?

Juxtaglomerular cells secrete renin in response to a drop in pressure detected by stretch receptors in the vascular walls, or when stimulated by macula densa cells. … When stimulated by epinephrine or norepinephrine, these receptors induce the secretion of renin.